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The FOXP3Delta2 isoform supports Treg cell development and protects against severe IPEX syndrome
Frith, K.; Joly, A. L.; Ma, C. S.; Tangye, S. G.; Lohse, Z.; Seitz, C.; Verge, C. F.; Andersson, J.; Gray, P.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 :317-320, 2019 10.1016/j.jaci.2019.03.003
Gallium-68-prostate-specific membrane antigen ((68) Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer
van Leeuwen, P. J.; Donswijk, M.; Nandurkar, R.; Stricker, P.; Ho, B.; Heijmink, S.; Wit, E. M. K.; Tillier, C.; van Muilenkom, E.; Nguyen, Q.; van der Poel, H. G.; Emmett, L.
BJU International 124 (1) :62-68, 2019 10.1111/bju.14506
African KhoeSan ancestry linked to high-risk prostate cancer
Petersen, D. C.; Jaratlerdsiri, W.; van Wyk, A.; Chan, E. K. F.; Fernandez, P.; Lyons, R. J.; Mutambirw, S. B. A.; van der Merwe, A.; Venter, P. A.; Bates, W.; Bornman, M. S. R.; Hayes, V. M.
BMC Medical Genomics 12 (1) :82, 2019 10.1186/s12920-019-0537-0
Estrogen receptor signaling is reprogrammed during breast tumorigenesis
Chi, D.; Singhal, H.; Li, L.; Xiao, T.; Liu, W.; Pun, M.; Jeselsohn, R.; He, H.; Lim, E.; Vadhi, R.; Rao, P.; Long, H.; Garber, J.; Brown, M.
A quantitative model to predict pathogenicity of missense variants in the TP53 gene
Fortuno, C.; Cipponi, A.; Ballinger, M. L.; Tavtigian, S. V.; Olivier, M.; Ruparel, V.; Haupt, Y.; Haupt, S.; Study, I. S. K.; Tucker, K.; Spurdle, A. B.; Thomas, D. M.; James, P. A.
HUMAN MUTATION 40 (6) :788-800, 2019 10.1002/humu.23739
Therapeutic implications of germline genetic findings in cancer
Thavaneswaran, S.; Rath, E.; Tucker, K.; Joshua, A. M.; Hess, D.; Pinese, M.; Ballinger, M. L.; Thomas, D. M.
Nature Reviews Clinical Oncology 16 (6) :386-396, 2019 10.1038/s41571-019-0179-3
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
Coll, R. C.; Hill, J. R.; Day, C. J.; Zamoshnikova, A.; Boucher, D.; Massey, N. L.; Chitty, J. L.; Fraser, J. A.; Jennings, M. P.; Robertson, A. A. B.; Schroder, K.
Nature Chemical Biology 15 (6) :556-559, 2019 10.1038/s41589-019-0277-7
The International Academy of Cytology Yokohama system for reporting breast fine-needle aspiration biopsy cytopathology
Field, A. S.; Raymond, W. A.; Rickard, M.; Arnold, L.; Brachtel, E. F.; Chaiwun, B.; Chen, L.; Di Bonito, L.; Kurtycz, D. F. I.; Lee, A. H. S.; Lim, E.; Ljung, B. M.; Michelow, P.; Osamura, R. Y.; Pinamonti, M.; Sauer, T.; Segara, D.; Tse, G.; Vielh, P.; Chong, P. Y.; Schmitt, F.
ACTA CYTOL 63 (4) :257-273, 2019 10.1159/000499509
beta Cell Hypoxia-Inducible Factor-1alpha Is Required for the Prevention of Type 1 Diabetes
Lalwani, A.; Warren, J.; Liuwantara, D.; Hawthorne, W. J.; O'Connell, P. J.; Gonzalez, F. J.; Stokes, R. A.; Chen, J.; Laybutt, D. R.; Craig, M. E.; Swarbrick, M. M.; King, C.; Gunton, J. E.
Cell Reports 27 (8) :2370-2384 e6, 2019 10.1016/j.celrep.2019.04.086
Longitudinal Changes in Insulin Resistance in Normal Weight, Overweight and Obese Individuals
Tang, A.; Coster, A. C. F.; Tonks, K. T.; Heilbronn, L. K.; Pocock, N.; Purtell, L.; Govendir, M.; Blythe, J.; Zhang, J.; Xu, A.; Chisholm, D. J.; Johnson, N. A.; Greenfield, J. R.; Samocha-Bonet, D.
Journal of Clinical Medicine 8 (5) :pii: E623, 2019 10.3390/jcm8050623
GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures
Styrkarsdottir, U.; Stefansson, O. A.; Gunnarsdottir, K.; Thorleifsson, G.; Lund, S. H.; Stefansdottir, L.; Juliusson, K.; Agustsdottir, A. B.; Zink, F.; Halldorsson, G. H.; Ivarsdottir, E. V.; Benonisdottir, S.; Jonsson, H.; Gylfason, A.; Norland, K.; Trajanoska, K.; Boer, C. G.; Southam, L.; Leung, J. C. S.; Tang, N. L. S.; Kwok, T. C. Y.; Lee, J. S. W.; Ho, S. C.; Byrjalsen, I.; Center, J. R.; Lee, S. H.; Koh, J. M.; Lohmander, L. S.; Ho-Pham, L. T.; Nguyen, T. V.; Eisman, J. A.; Woo, J.; Leung, P. C.; Loughlin, J.; Zeggini, E.; Christiansen, C.; Rivadeneira, F.; van Meurs, J.; Uitterlinden, A. G.; Mogensen, B.; Jonsson, H.; Ingvarsson, T.; Sigurdsson, G.; Benediktsson, R.; Sulem, P.; Jonsdottir, I.; Masson, G.; Holm, H.; Norddahl, G. L.; Thorsteinsdottir, U.; Gudbjartsson, D. F.; Stefansson, K.
Nature Communications 10 (1) :2054, 2019 10.1038/s41467-019-09860-0
Dietary intake of people with severe mental illness: systematic review and meta-analysis
Teasdale, S. B.; Ward, P. B.; Samaras, K.; Firth, J.; Stubbs, B.; Tripodi, E.; Burrows, T. L.
Br J Psychiatry 214 (5) :251-259, 2019 10.1192/bjp.2019.20
Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells
Lukowski, S. W.; Patel, J.; Andersen, S. B.; Sim, S. L.; Wong, H. Y.; Tay, J.; Winkler, I.; Powell, J. E.; Khosrotehrani, K.
Cell Reports 27 (9) :2748-2758.e3, 2019 10.1016/j.celrep.2019.04.102
Cyclin Dependent Kinase 2 inhibitors in cancer therapy: an update
Tadesse, S.; Caldon, E. C.; Tilley, W.; Wang, S.
JOURNAL OF MEDICINAL CHEMISTRY 62 (9) :4233-4251, 2019 10.1021/acs.jmedchem.8b01469
Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP
Tangye, S. G.; Bucciol, G.; de Las Casas, J. M.; Pillay, B.; Ma, C. S.; Moens, L.; Meyts, I.
IMMUNOLOGY AND CELL BIOLOGY 97 (4) :389-402, 2019 10.1111/imcb.12243