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Heparan sulfate proteoglycans in beta cells provide a critical link between endoplasmic reticulum stress, oxidative stress and type 2 diabetes
Dhounchak, S.; Popp, S. K.; Brown, D. J.; Laybutt, D. R.; Biden, T. J.; Bornstein, S. R.; Parish, C. R.; Simeonovic, C. J.
PLoS One 16 (6) :e0252607, 2021 10.1371/journal.pone.0252607
Proteogenomic analysis of Inhibitor of Differentiation 4 (ID4) in basal-like breast cancer
Baker, L. A.; Holliday, H.; Roden, D.; Krisp, C.; Wu, S. Z.; Junankar, S.; Serandour, A. A.; Mohammed, H.; Nair, R.; Sankaranarayanan, G.; Law, A. M. K.; McFarland, A.; Simpson, P. T.; Lakhani, S.; Dodson, E.; Selinger, C.; Anderson, L.; Samimi, G.; Hacker, N. F.; Lim, E.; Ormandy, C. J.; Naylor, M. J.; Simpson, K.; Nikolic, I.; O'Toole, S.; Kaplan, W.; Cowley, M. J.; Carroll, J. S.; Molloy, M.; Swarbrick, A.
BREAST CANCER RES 22 (1) :63, 2021 10.1186/s13058-020-01306-6
Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish
Buono, L.; Corbacho, J.; Naranjo, S.; Almuedo-Castillo, M.; Moreno-Marmol, T.; de la Cerda, B.; Sanbria-Reinoso, E.; Polvillo, R.; Diaz-Corrales, F. J.; Bogdanovic, O.; Bovolenta, P.; Martinez-Morales, J. R.
Nature Communications 12 (1) :3866, 2021 10.1038/s41467-021-24169-7
Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup
O'Sullivan, J. M.; den Heijer, J. M.; Groeneveld, G. J.; Cooper, A. A.
MOVEMENT DISORDERS 36 (6) :1468-1470, 2021 10.1002/mds.28620
Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis
Park, S. J.; Ahmad, F.; Bahde, R. J.; Philp, A.; Kim, J.; Huang, T.; Kim, M. K.; Trenkle, W. C.; Chung, J. H.
PLoS One 16 (6) :e0253269, 2021 10.1371/journal.pone.0253269
Ninjin'yoeito modulates feeding and activity under negative energy balance conditions via the NPY system
Zhang, L.; Clark, T.; Gopalasingam, G.; Neely, G. G.; Herzog, H.
NEUROPEPTIDES 87 :102149, 2021 10.1016/j.npep.2021.102149
SARS-CoV-2-related MIS-C: A key to the viral and genetic causes of Kawasaki disease?
V. Sancho-Shimizu, P. Brodin, A. Cobat, C.M. Biggs, J. Toubiana, C.L. Lucas, S.E. Henrickson, A. Belot, , S.G. Tangye, J.D. Milner, M. Levin, L. Abel, D. Bogunovic, J.L. Casanova, and S.Y. Zhang
JOURNAL OF EXPERIMENTAL MEDICINE 218 (6) 2021 10.1084/jem.20210446
A Selective Look at Autophagy in Pancreatic beta-Cells
Pearson, G. L.; Gingerich, M. A.; Walker, E. M.; Biden, T. J.; Soleimanpour, S. A.
DIABETES 70 (6) :1229-1241, 2021 10.2337/dbi20-0014
A novel signature predicts recurrence risk and therapeutic response in breast cancer patients
Tran, Q. H.; Than, V. T.; Luu, P. L.; Clarke, D.; Lam, H. N.; Nguyen, T. T.; Nguyen, D. T.; Duy, P. Q.; Phung, D.; Nguyen, M. N.
INTERNATIONAL JOURNAL OF CANCER 148 (11) :2848-2856, 2021 10.1002/ijc.33512
Inhibition of guanosine monophosphate synthetase (GMPS) blocks glutamine metabolism and prostate cancer growth
Wang, Q.; Guan, Y. F.; Hancock, S. E.; Wahi, K.; van Geldermalsen, M.; Zhang, B. K.; Pang, A.; Nagarajah, R.; Mak, B.; Freidman, N.; Horvath, L. G.; Turner, N.; Holst, J.
JOURNAL OF PATHOLOGY 254 (2) :135-146, 2021 10.1002/path.5665
Low repeatability of aversive learning in zebrafish (Danio rerio)
Mason, D.; Zajitschek, S.; Anwer, H.; O'Dea, R. E.; Hesselson, D.; Nakagawa, S.
JOURNAL OF EXPERIMENTAL BIOLOGY 224 (11) 2021 10.1242/jeb.240846
Transcriptome analysis of islets from diabetes-resistant and diabetes-prone obese mice reveals novel gene regulatory networks involved in beta-cell compensation and failure
Chan, J. Y.; Bensellam, M.; Lin, R. C. Y.; Liang, C.; Lee, K.; Jonas, J. C.; Laybutt, D. R.
FASEB JOURNAL 35 (6) :e21608, 2021 10.1096/fj.202100009R
An efficient new assay for measuring zebrafish anxiety: Tall tanks that better characterize between-individual differences
Anwer, H.; Mason, D.; Zajitschek, S.; Noble, D. W. A.; Hesselson, D.; Morris, M. J.; Lagisz, M.; Nakagawa, S.
JOURNAL OF NEUROSCIENCE METHODS 356 :109138, 2021 10.1016/j.jneumeth.2021.109138
CD8(+) T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph
Hensen, L.; Illing, P. T.; Bridie Clemens, E.; Nguyen, T. H. O.; Koutsakos, M.; van de Sandt, C. E.; Mifsud, N. A. Nguyen, A. T.; Szeto, C.; Chua, B. Y.; Halim, H.; Rizzetto, S.; Luciani, F.; Loh, L.; Grant, E. J.; Saunders, P. M.; Brooks, A. G.; Rockman, S.; Kotsimbos, T. C.; Cheng, A. C.; Richards, M.; Westall, G. P.; Wakim, L. M.; Loudovaris, T.; Mannering, S. I.; Elliott, M.; Tangye, S. G.; Jackson, D. C.; Flanagan, K. L.; Rossjohn, J.; Gras, S.; Davies, J.; Miller, A.; Tong, S. Y. C.; Purcell, A. W.; Kedzierska, K.
Nature Communications 12 (1) :2931, 2021 10.1038/s41467-021-23212-x
DNA methylation profiles unique to Kalahari KhoeSan individuals
Goncearenco, A.; LaBarre, B. A.; Petrykowska, H. M.; Jaratlerdsiri, W.; Bornman, M. S. R.; Turner, S. D.; Hayes, V. M.; Elnitski, L.
Epigenetics :1-17, 2021 10.1080/15592294.2020.1809852