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5106 items matching your search terms.

The role of inflammation and endoplasmic reticulum stress in obesity-related cognitive impairment: Liu, Y.; Yu, J.; Shi, Y. C.; Zhang, Y.; Lin, S.; LIFE SCIENCES 233 :116707, 2019 10.1016/j.lfs.2019.116707

Accurate detection of m(6)A RNA modifications in native RNA sequences: Liu, H.; Begik, O.; Lucas, M. C.; Ramirez, J. M.; Mason, C. E.; Wiener, D.; Schwartz, S.; Mattick, J. S.; Smith, M. A.; Novoa, E. M.; Nature Communications 10 (1) :4079, 2019 10.1038/s41467-019-11713-9

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan: Vennin, C.; Melenec, P.; Rouet, R.; Nobis, M.; Cazet, A. S.; Murphy, K. J.; Herrmann, D.; Reed, D. A.; Lucas, M. C.; Warren, S. C.; Elgundi, Z.; Pinese, M.; Kalna, G.; Roden, D.; Samuel, M.; Zaratzian, A.; Grey, S. T.; Da Silva, A.; Leung, W.; Mathivanan, S.; Wang, Y.; Braithwaite, A. W.; Christ, D.; Benda, A.; Parkin, A.; Phillips, P. A.; Whitelock, J. M.; Gill, A. J.; Sansom, O. J.; Croucher, D. R.; Parker, B. L.; Pajic, M.; Morton, J. P.; Cox, T. R.; Timpson, P.; Nature Communications 10 (1) :3637, 2019 10.1038/s41467-019-10968-6

Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes-cardiovascular and renal benefits in patients with chronic kidney disease: Milder, T. Y.; Stocker, S. L.; Samocha-Bonet, D.; Day, R. O.; Greenfield, J. R.; EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 2019 10.1007/s00228-019-02732-y

Use of synthetic DNA spike-in controls (sequins) for human genome sequencing: Blackburn, J.; Wong, T.; Madala, B. S.; Barker, C.; Hardwick, S. A.; Reis, A. L. M.; Deveson, I. W.; Mercer, T. R.; Nature Protocols 14 (7) :2119-2151, 2019 10.1038/s41596-019-0175-1

Multilayered control of exon acquisition permits the emergence of novel forms of regulatory control: Avgan, N.; Wang, J. I.; Fernandez-Chamorro, J.; Weatheritt, R. J.; GENOME BIOLOGY 20 (1) :141, 2019 10.1186/s13059-019-1757-5

The FOXP3Delta2 isoform supports Treg cell development and protects against severe IPEX syndrome: Frith, K.; Joly, A. L.; Ma, C. S.; Tangye, S. G.; Lohse, Z.; Seitz, C.; Verge, C. F.; Andersson, J.; Gray, P.; JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 :317-320, 2019 10.1016/j.jaci.2019.03.003

Methylome and transcriptome maps of human visceral and subcutaneous adipocytes reveal key epigenetic differences at developmental genes: Bradford, S. T.; Nair, S. S.; Statham, A. L.; van Dijk, S. J.; Peters, T. J.; Anwar, F.; French, H. J.; von Martels, J. Z. H.; Sutcliffe, B.; Maddugoda, M. P.; Peranec, M.; Varinli, H.; Arnoldy, R.; Buckley, M.; Ross, J. P.; Zotenko, E.; Song, J. Z.; Stirzaker, C.; Bauer, D. C.; Qu, W.; Swarbrick, M. M.; Lutgers, H. L.; Lord, R. V.; Samaras, K.; Molloy, P. L.; Clark, S. J.; Scientific Reports 9 (1) :9511, 2019 10.1038/s41598-019-45777-w

Gallium-68-prostate-specific membrane antigen ((68) Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer: van Leeuwen, P. J.; Donswijk, M.; Nandurkar, R.; Stricker, P.; Ho, B.; Heijmink, S.; Wit, E. M. K.; Tillier, C.; van Muilenkom, E.; Nguyen, Q.; van der Poel, H. G.; Emmett, L.; BJU International 124 (1) :62-68, 2019 10.1111/bju.14506

Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4(+) T cells: Bier, J.; Rao, G.; Payne, K.; Brigden, H.; French, E.; Pelham, S. J.; Lau, A.; Lenthall, H.; Edwards, E. S. J.; Smart, J. M.; Cole, T. S.; Choo, S.; Joshi, A. Y.; Abraham, R. S.; O'Sullivan, M.; Boztug, K.; Meyts, I.; Gray, P. E.; Berglund, L. J.; Hsu, P.; Wong, M.; Holland, S. M.; Notarangelo, L. D.; Uzel, G.; Ma, C. S.; Brink, R.; Tangye, S. G.; Deenick, E. K.; JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 (1) :236-253, 2019 10.1016/j.jaci.2019.01.033

African KhoeSan ancestry linked to high-risk prostate cancer: Petersen, D. C.; Jaratlerdsiri, W.; van Wyk, A.; Chan, E. K. F.; Fernandez, P.; Lyons, R. J.; Mutambirw, S. B. A.; van der Merwe, A.; Venter, P. A.; Bates, W.; Bornman, M. S. R.; Hayes, V. M.; BMC Medical Genomics 12 (1) :82, 2019 10.1186/s12920-019-0537-0

Estrogen receptor signaling is reprogrammed during breast tumorigenesis: Chi, D.; Singhal, H.; Li, L.; Xiao, T.; Liu, W.; Pun, M.; Jeselsohn, R.; He, H.; Lim, E.; Vadhi, R.; Rao, P.; Long, H.; Garber, J.; Brown, M.; PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116 (23) :11437-11443, 2019 10.1073/pnas.1819155116

A quantitative model to predict pathogenicity of missense variants in the TP53 gene: Fortuno, C.; Cipponi, A.; Ballinger, M. L.; Tavtigian, S. V.; Olivier, M.; Ruparel, V.; Haupt, Y.; Haupt, S.; Study, I. S. K.; Tucker, K.; Spurdle, A. B.; Thomas, D. M.; James, P. A.; HUMAN MUTATION 40 (6) :788-800, 2019 10.1002/humu.23739

Therapeutic implications of germline genetic findings in cancer: Thavaneswaran, S.; Rath, E.; Tucker, K.; Joshua, A. M.; Hess, D.; Pinese, M.; Ballinger, M. L.; Thomas, D. M.; Nature Reviews Clinical Oncology 16 (6) :386-396, 2019 10.1038/s41571-019-0179-3

MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition: Coll, R. C.; Hill, J. R.; Day, C. J.; Zamoshnikova, A.; Boucher, D.; Massey, N. L.; Chitty, J. L.; Fraser, J. A.; Jennings, M. P.; Robertson, A. A. B.; Schroder, K.; Nature Chemical Biology 15 (6) :556-559, 2019 10.1038/s41589-019-0277-7

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